Pyruvate dehydrogenase complex deficiency (PDCD) is a rare disorder of carbohydrate metabolism caused by a deficiency of one of the three enzymes in the pyruvate dehydrogenase complex (PDC). The age of onset and severity of disease symptoms vary widely. Individuals with PDCD symptom onset in the prenatal period or in infancy usually die in
Complications such as heart arrhythmias, cardiac contractile function impairment, sudden death, osteoporosis, kidney damage, increased cancer risk, impairment of physical activity and lipid abnormalities can all be linked to long-term restriction of carbohydrates in the diet. The need to further explore and communicate the untoward side-effectsNutritional disease - Carbohydrates, Deficiencies, Malnutrition: Under most circumstances, there is no absolute dietary requirement for carbohydrates—simple sugars, complex carbohydrates such as starches, and the indigestible plant carbohydrates known as dietary fibre. Certain cells, such as brain cells, require the simple carbohydrate glucose as fuel. If dietary carbohydrate is insufficient
Infants rarely develop serious and obvious G6PD deficiency symptoms. The most common symptom is severe jaundice that appears within an infant’s first 24 hours and/or an infant has a bilirubin level that’s greater than the 95th percentile. Left untreated, infants with severe jaundice can develop brain damage. . 182 383 344 362 179 22 183 331